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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMF1
All Species:
19.7
Human Site:
S274
Identified Species:
27.08
UniProt:
P82094
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P82094
NP_009045.2
1093
122842
S274
V
I
S
E
S
S
A
S
S
R
Q
E
T
T
D
Chimpanzee
Pan troglodytes
XP_526227
1093
122795
S274
V
I
S
E
S
S
A
S
S
R
Q
E
T
T
D
Rhesus Macaque
Macaca mulatta
XP_001088711
1092
122828
S273
V
I
S
E
S
S
A
S
S
R
Q
E
T
T
D
Dog
Lupus familis
XP_533766
1089
122761
R272
S
E
S
S
A
S
S
R
Q
E
T
T
D
S
K
Cat
Felis silvestris
Mouse
Mus musculus
B9EKI3
1091
121796
R272
S
E
S
S
A
S
S
R
Q
E
T
S
D
A
K
Rat
Rattus norvegicus
NP_446123
1093
121882
R273
S
E
S
S
A
S
S
R
Q
E
T
S
D
A
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510334
1106
124384
S280
V
I
S
E
S
S
A
S
S
R
Q
E
A
A
D
Chicken
Gallus gallus
O42184
1433
161009
R372
I
E
Q
L
L
A
E
R
D
L
E
R
A
E
V
Frog
Xenopus laevis
Q5PQ23
649
75475
Zebra Danio
Brachydanio rerio
NP_001003522
1136
126986
S300
V
L
S
E
S
S
A
S
S
R
Q
E
T
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572360
933
103794
M224
F
E
D
I
Q
L
Q
M
S
H
K
G
K
S
P
Honey Bee
Apis mellifera
XP_394037
1326
150590
V313
L
V
T
S
P
S
S
V
E
V
L
G
D
W
K
Nematode Worm
Caenorhab. elegans
P02566
1966
225108
S905
S
L
F
T
N
L
E
S
T
K
T
Q
L
S
D
Sea Urchin
Strong. purpuratus
XP_785821
1176
131318
D279
R
E
F
E
E
E
N
D
T
L
V
D
Q
P
L
Poplar Tree
Populus trichocarpa
XP_002303293
975
109171
A267
S
S
D
T
R
A
G
A
V
L
D
S
S
S
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q0WVL7
956
108335
E248
E
I
L
G
E
N
L
E
G
R
T
S
S
K
N
Baker's Yeast
Sacchar. cerevisiae
P47166
707
81153
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.5
93.1
N.A.
87.2
86.7
N.A.
81.2
21.7
22.6
59.7
N.A.
26.1
23.9
21
37.7
Protein Similarity:
100
99.4
99.1
96.1
N.A.
92.5
92
N.A.
88.3
39.9
37.3
74.6
N.A.
45.8
44.9
36.6
56.8
P-Site Identity:
100
100
100
13.3
N.A.
13.3
13.3
N.A.
86.6
0
0
80
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
100
100
33.3
N.A.
26.6
26.6
N.A.
86.6
20
0
93.3
N.A.
20
33.3
53.3
20
Percent
Protein Identity:
25.8
N.A.
N.A.
27.1
21.1
N.A.
Protein Similarity:
47.2
N.A.
N.A.
45.4
39.4
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
18
12
30
6
0
0
0
0
12
24
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
12
0
0
0
0
6
6
0
6
6
24
0
30
% D
% Glu:
6
36
0
36
12
6
12
6
6
18
6
30
0
6
6
% E
% Phe:
6
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
6
0
0
6
0
6
0
0
12
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% H
% Ile:
6
30
0
6
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
6
6
0
6
6
24
% K
% Leu:
6
12
6
6
6
12
6
0
0
18
6
0
6
0
6
% L
% Met:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
6
6
6
0
0
0
0
0
0
0
6
% N
% Pro:
0
0
0
0
6
0
0
0
0
0
0
0
0
6
6
% P
% Gln:
0
0
6
0
6
0
6
0
18
0
30
6
6
0
0
% Q
% Arg:
6
0
0
0
6
0
0
24
0
36
0
6
0
0
0
% R
% Ser:
30
6
48
24
30
53
24
36
36
0
0
24
12
24
6
% S
% Thr:
0
0
6
12
0
0
0
0
12
0
30
6
24
18
0
% T
% Val:
30
6
0
0
0
0
0
6
6
6
6
0
0
0
6
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
6
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _